Aug 13, 2025 · Sickle cell disease (SCD) is an inherited blood disorder. It causes your red blood cells to form into a “C” shape. It can cause pain and serious complications.

Find sickle cell disease-related data and statistics on prevalence, complications, and more. Find fact sheets, toolkits, infographics and more on sickle cell disease and sickle cell trait. Learn the steps …

What is sickle cell disease? Sickle cell disease (SCD) is an inherited blood disorder. That means it is passed down from a parent’s genes. It causes the body to make abnormal hemoglobin. Hemoglobin …

Since 1972, our organization has been on the forefront of improving the quality of health, life and services for individuals, families and communities affected by this rare disease and related …

In September 2024, Pfizer withdrew voxelotor (also called Oxbryta) from the market. The medicine was used to prevent sickling in red blood cells. Pfizer said the benefits of using voxelotor do not outweigh …

Aug 6, 2025 · Sickle-cell disease (SCD) is a genetic disorder that affects haemoglobin, the molecule in red blood cells responsible for carrying oxygen. The disease causes red blood cells to become rigid …

Feb 21, 2025 · Sickle cell disease (SCD) is a group of inherited blood disorders. Abnormal hemoglobin is produced. Red blood cells become hard and sticky and get stuck in small blood vessels, resulting …

May 15, 2024 · In people with SCD, red blood cells become rigid and deform into a crescent or sickle shape. Sickled cells die early and often become lodged in small blood vessels, restricting blood flow, …

Sep 6, 2024 · What causes sickle cell disease (SCD)? SCD is caused by a variant (change) in a gene that has instructions for your body to make one part of the hemoglobin. This changed gene is …

Aug 28, 2024 · Sickle cell disease (SCD) is a blood disorder present at birth. People with SCD have sickle-shaped red blood cells that stick together and block blood and oxygen from reaching all parts …