Encephalitis is an inflammation of the brain that can be caused by infections or autoimmune reactions. Even when patients survive the acute phase, many are left with long-lasting neurological problems ...

One of the most detailed 3D maps of how the human chromosomes are organized and folded within a cell's nucleus is published in Nature. Chromosomes are thread-like structures that carry a cell's ...

Abstract: Chromatin encompasses a variety of three-dimensional structures with distinct forms and ranges, among which chromatin loops play a crucial role in gene regulatory mechanisms and the ...

Over the past few decades, advances in hematology have illuminated how a delicate balance between stem cell self-renewal and differentiation sustains healthy blood formation. In myelodysplastic ...

High-resolution imaging has revealed the internal layout of chromatin condensates, showing how DNA fibers fold and interact within these droplet-like structures. The findings connect molecular ...

New ultra-detailed imaging exposes the hidden structure and behavior of chromatin condensates — and hints at how their failures may drive disease. Credit: Shutterstock Six feet of human DNA crammed ...

Reconstructed image of the basic unit of chromatin, the nucleosome. Nucleosomes link together like beads on a string, connected by stretches of linker DNA. To form a condensate, these strings bind ...

New work shows that physical folding of the genome to control genes located far away may have been a critical turning point for life on Earth. For evolutionary biologists, what most distinguishes the ...