Cholera remains a major global public health challenge, with an estimated 1.3 to 4 million cases and tens of thousands of ...

Metabolism, far from being just a housekeeping function, underlies all changes in cell size and function ...

UCSF scientists engineered old fibroblast cells to turn their genes on and off in the same way as young fibroblasts. The old ...

A new CRISPR-based approach for tuning gene expression up and down allowed identification of how other genes' expression responds to changes of transcription factors.

CSIC, reveals how the bacterium that causes cholera activates its virulence programme, uncovering a single amino acid as a ...

UMass Chan Medical School scientists have nearly tripled the known number of potential regulatory elements in the genome to 2 ...

As we age, we don't recover from injury or illness like we did when we were young. But new research from UCSF has found gene ...

Plant regeneration relies on a delicate balance between stem cell renewal and differentiation, yet the evolutionary origin ...

Leaf senescence determines the duration of photosynthesis, nutrient remobilization efficiency, and ultimately crop yield and ...

Precision and timing of gene expression is essential for normal biological functions and, when disrupted, can lead to many ...

Agriculture, from the outset, has been made possible by humans tweaking the genes of plants to make them grow faster, produce more of what we want, and survive drought, pests, and infection. For ...

Thanks to a first-of-its-kind platform, we are starting to understand how the molecular engine responsible for transcription in mammals controls its speed. A team of researchers from The Rockefeller ...