Individual genes express multiple mRNAs by pre-mRNA alternative splicing, alternative polyadenylation or use of alternative promoters (first exons). As a result, individual genes express multiple ...
Widespread alterations in RNA processing (splicing, polyadenylation, decay, etc.) are common in dynamic cell states during development and malignancy. For example, many cancers harbor elevated levels ...
The spliceosome in eukaryotes removes non-coding intronic sequences and ligates exons to produce functional messenger ribonucleic acids (mRNA) that code for proteins. However, while numerous studies ...
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