Scientists at St. Jude Children's Research Hospital have characterized a hidden intermediate state at the center of Src ...
News-Medical.Net on MSN
Hidden kinase state enables rapid and repeated protein phosphorylation
Scientists at St. Jude Children's Research Hospital have characterized a hidden intermediate state at the center of Src kinase function. This hidden state allows the kinase to repeatedly modify its ...
AZoLifeSciences on MSN
Elusive kinase state explains how cells achieve efficient signaling
Scientists at St. Jude Children's Research Hospital have characterized a hidden intermediate state at the center of Src ...
News Medical on MSN
JMC Publication: Insilico’s AI platforms enable discovery of potent, selective, oral DGKα inhibitor to overcome checkpoint resistance
Novel, Potent, Selective and Orally Available DGKα Inhibitors for the Treatment of Tumors view more . Credit: Insilico ...
Researchers from the University of Arizona have uncovered how a protein complex, known for regulating cell growth and adjusting metabolism, functions in a more complex manner.
When a cell receives a message from outside, it generates a molecule called cyclic AMP (cAMP) to relay this message. To ensure the signal reaches the correct effector without triggering pathways ...
Secura Bio, Inc. ( an integrated pharmaceutical company maximizing commercial outcomes for oncology medicines, today provided a corporate update, including an update on the encouraging enrollment ...
Overall, the reviewers wrote, most IBD therapies “appear safe and effective when used in chronic kidney disease, including on ...
Cogent Biosciences (COGT) shares have surged after pivotal bezuclastinib data in imatinib-resistant aGIST. Read the latest ...
Due to the extremely rare overlap of mitochondrial DNA depletion syndrome type 3 and pediatric hepatocellular carcinoma, the case presents daunting therapeutic challenges.
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