eLife

Cytoplasmatic polyadenylation of mRNA by TENT5A is critical for enamel mineralization

This study reports an important and novel finding that TENT5A, an enzyme involved in fine-tuning poly(A) tail length on selected mRNAs, is required for proper enamel mineralization in mice. The ...
ascopubs.org

HER2 Protein Overexpression, mRNA Expression, and DNA Amplification Across Solid Tumors: Comparison of Next-Generation Sequencing–Based Assays With Immunohistochemistry

Real-World Plasma Thymidine Kinase Activity in High-Risk and Metastatic Hormone Receptor–Positive, Human Epidermal Growth Factor Receptor 2–Negative Breast Cancer Treated With Cyclin-Dependent Kinase ...
ascopubs.org

Epidemiology of MET gene mRNA expression in metastatic colorectal cancer: Analyses of a real-world clinicogenomic database.

Recent trends in cancer distribution and survival outcomes among adolescent and young adult patients: A national data analysis.
eLife

Ribosome demand links transcriptional bursts to protein expression noise

Propagation of expression noise from mRNA to protein level is influenced by variation in availability of ribosomal machinery.