The voltage-gated potassium channels (Kv) are partially responsible for the contraction/relaxation of blood vessels in response to changes in the Po 2 level. The ...

Potassium channels are openings that allow charged potassium atoms to cross the cell membrane. Voltage-gated potassium channels—which open only when a specific voltage is reached across the cell ...

Pregnant ewes were obtained at 118 ± 2 d of gestation. After a period of acclimation, ewes underwent midline laparotomy and hysterotomy under general anesthesia at 128 ± 2 d gestation. Fetal chest was ...

Orphan Drug Designation applies to approximately 50,000 Patients who predominantly suffer from severe chronic pain due to ...

Researchers from École Polytechnique Fédérale de Lausanne, Switzerland (EPFL) have mapped the molecular workings of potassium ion channels within the brain. The study titled, “A kinetic map of the ...

Autifony Therapeutics Ltd. has described compounds acting as modulators of voltage-gated potassium channels from the Kv3 subfamily, such as Kv3.1, Kv3.2 and/or Kv3.3, reported to be useful for the ...

Kv7.2/7.3 channels are voltage-gated potassium channels involved in regulating membrane potential and neuronal excitability.

Researchers form Shanghai Zhimeng Biopharma Inc. presented preclinical data for CB-03, a voltage-gated potassium channel-2/3 (Kv7.2/Kv7.3; KCNQ2/3) opener for the treatment of patients with refractory ...

The process of expressing a wide variety of voltage-gated and ligand-gated ion channels enables nociceptors to transduce receptor potential into single action potentials or multiple action potentials.