Spatial MALDI-MSI of osteoarthritic knee joints reveals bone-derived protein signatures linked to disease progression. These candidates will be validated in larger patient cohorts and OA mouse models ...
Sympathetic nerves precede sensory nerves and run in parallel with sensory nerves in the subchondral bone of TMJ-OA mice. During the early stage of TMJ-OA, regional sympathetic nerves release ...
Osteoarthritis often goes undetected until cartilage damage is advanced, limiting treatment options. A new study shows that molecular changes in subchondral bone occur earlier and can signal disease ...
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