The question of putative mechanisms of action continues to haunt psychopharmacology. Put simply, we know these drugs work, but we have very little idea how. We make guesses based on the neurochemical ...

Selective Serotonin Reuptake Inhibitors (SSRIs) were introduced in 1987 with the release of Prozac, and since then have become the most common type of antidepressant used by Americans. According to ...