There’s been this dream for decades. What if we could just print out an entire gene directly, one base at a time? —Daniel Lin-Arlow, Ansa Biotechnologies As scientists set their sights on cell and ...

Depurination of DNA and RNA sequences is an alteration of the sugar-phosphate backbone in which hydrolysis of a purine base (adenine or guanine) occurs. Synthetic oligonucleotides suffer from such ...

Therapeutic oligonucleotides act on different stages of pathological gene expression. Standard schematic of oligonucleotide activities in pathogenesis disease progression. Decoys bind to transcription ...

Next-generation gene synthesis could be as transformative for several multibillion-dollar industries as the semiconductor. Over the past 60 years researchers have spent a great deal of time and money ...