A clinical trial on the VIA Disc NP treatment for discogenic back pain has shown impressive results, significantly reducing pain and improving back function. The non-surgical, minimally invasive ...
This integrated approach, combining histological analysis and single-nucleus RNA sequencing, revealed that the senescence and depletion of nucleus pulposus progenitor cells (NPPCs) represent ...
Schematic diagram depicting the mechanism of the rigid matrix regulating cell glycolysis in degenerated NPCs. In degenerated NP tissue, MRTF-A was activated by increased matrix stiffness and ...
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