Article reviewed by Govind Kaigala, PhD at the University of British Columbia. Stay up to date on the latest science with Brush Up Summaries. In situ hybridization (ISH) is a molecular technique that ...

Fluorescence in situ hybridisation (FISH) has long been established as an indispensable molecular tool for the detection, localisation and quantification of nucleic acids within their native cellular ...

Guanine quadruplexes (G-quadruplexes or G4s) are unusual nucleic acid structures with distinct biological and chemical functions. They have occupied significant attention in the nucleic acid world ...

In the case of nucleic acid tests, polymerase chain reaction (PCR) has been the gold standard for single-molecule diagnosis. Single-molecule detection of pathogens, such as severe acute respiratory ...