Cells have surface receptors that couple with proteins and other molecules to initiate or inhibit certain behaviors. Typically, the number of these receptors increases as the cell matures, but ...

Duke University Medical Center-led research has identified a human-specific DNA enhancer that regulates neural progenitor proliferation and cortical size. Small genetic changes in HARE5 amplify a key ...

In a new study from Karolinska Institutet, published in Nature Neuroscience, researchers have identified the neurogenic progenitor that gives rise to dopaminergic neurons, the primary neurons affected ...

A new discovery by neuroscientists at Brown University's Carney Institute for Brain Science challenges long-held beliefs in ...

A new study in zebrafish reveals that the gene nexmifb—a paralog of the human neurodevelopmental gene NEXMIF—plays a critical role in spinal motor neuron development by modulating the axon guidance ...

Dopaminergic neurons arise from progenitor cells in the ventral midbrain under the coordinated influence of morphogens such as Sonic Hedgehog, Wnt and FGF, and the action of transcription factors ...

UCLA researchers created a single-cell map of the developing human neocortex in Down syndrome during a critical window of prenatal brain development, finding that the condition alters the ...

To better model how neurons fire and interact with glia, some scientists place the cells into a brain or grow them in an organoid. Others have produced little spheres of human neural tissue by ...