The final weeks in the NFL are coming in the 2025 season. And although the current NFL playoff picture is very much muddled, there are actual postseason spots up for grabs in Week 16.

Colts quarterback Philip Rivers should face less pressure his second week back in the NFL, as his team plays the 49ers on "Monday Night Football."

Two teams firmly on the playoff bubble highlight Sunday's slate as Pittsburgh travels to Detroit, but what NFL action will be available in your area?

Who is playing on Monday Night Football? Check out the complete MNF game schedule, including 49ers vs Colts matchup for NFL Week 16 game on Dec. 22.

In Week 15, there were four games with double-digit spreads, and 44-year-old Philip Rivers helped lead his team to the only cover among those underdogs. He's already a betting spread legend.

Bills (10-4, -10 1/2) over @Browns (3-11), 28-16: Buffalo, buoyed by huge rally triumph in New England, can clinch playoffs with win here if Texans and Colts also lose. More important, Bills still chase AFC East title and won’t let lowly Browns get in way. Josh Allen keeps showing he can beat anything ... including his own middling defense.

Another week of NFL action kicks off on Thursday, December 18, with a primetime showdown in the NFC West with the Seattle Seahawks playing host to the Los Angeles Rams. It’s a battle of two of the best teams in the NFC, with both franchises bringing an ...

Week 16 in the NFL features a loaded afternoon slate with 11 games. Featured in the early window, the Tampa Bay Buccaneers and Carolina Panthers fight it out over first place in the NFC South.