Inspired by the natural bonding between a class of potent local anesthetics called site-1 sodium channel blockers (S1SCBs) and peptide sequences on the sodium channel in the nerve cell membrane, ...

Advocates urge clinicians to consult with elective surgery patients about local anesthetics shortages, the potential health risks, and alternative forms of pain management. A global shortage of local ...

Surgery in your future? We know what you’re probably thinking: Just knock me out. Here, however, dermatologist A. David Rahimi, MD, discusses why you should strongly consider local anesthesia instead ...

Local anesthetics have transformed clinical practice by enabling a broad range of minor and major procedures with minimal discomfort. Although adverse reactions are frequently reported, genuine ...

The localized loss of sensation with resultant reduction in pain stimuli is the end result of local anesthesia. This mode of anesthesia is considered to be safer than general anesthesia, because it ...

NEW ORLEANS, LA—Going with a minimalist approach that involves local instead of general anesthesia appears to have several advantages for patients undergoing TAVR, according to a new meta-analysis. In ...

Local anesthetics bupivacaine and lidocaine have been in unsteady supply since at least 2015, and recently, drugmakers postponed their expected resupply dates again. For six of Pfizer’s bupivacaine ...

There is a real need in the treatment of postoperative pain and in the management of problems of intractable pain for local anesthetics with a duration of action longer than six to eight hours, the ...

Aging hearing loss is a disease that gradually becomes difficult to hear due to the regression of the auditory organs, ...

Deaths from lidocaine poisonings more than doubled since 2010, calls to poison control centers suggested. Calls about local anesthetic poisonings decreased by 23%, mainly due to fewer non-lidocaine ...

Anesthesiology saw a year of significant innovation in 2025 as new technologies, techniques and care models redefined what is possible in the perioperative environment. From AI-driven automation to ...

Universitätsmedizin Berlin has reduced the annual CO2 emissions originating from gases used for anesthesia by over 80% since 2018. This reduction in carbon emissions was achieved by using ...