Elevated baseline LDH levels predict worse clinical outcomes in heart failure with reduced ejection fraction and modestly ...
Blood lactate is influenced by a wide range of metabolic processes. Blood lactate—much like central venous pressure—can ...
COOH) represents the protonated form of the organic acid, whereas lactate (CH₃CH (OH)COO⁻) represents its conjugated base.
Elevated white blood cell counts also appear to correlate with shorter overall survival in patients receiving standard induction chemotherapy plus cytarabine for acute myeloid leukemia. High serum ...
Patients with paroxysmal nocturnal hemoglobinuria (PNH) had decreased quality of life (QOL) and worse fatigue that could be linked to lactate dehydrogenase levels. Researchers found that levels of ...
A meta-analysis of two randomized, double-blind, placebo-controlled, phase III studies in patients (pts) with metastatic colorectal cancer (mCRC) receiving FOLFOX4 and PTK/ZK to determine clinical ...
Background Lactate dehydrogenase (LDH) isoenzymes are required for adenosine triphosphate production, with each of five different isoenzymes having varying proficiencies in anaerobic versus aerobic ...
Dynamic angiogenic switch as predictor of response to chemotherapy+ bevacizumab in patients with metastatic colorectal cancer. This is an ASCO Meeting Abstract from the 2016 ASCO Annual Meeting I.
The Warburg effect describes how cancer cells switch from oxidative phosphorylation to glycolysis even in oxygen-rich conditions, producing massive amounts of lactate that accumulate in the tumor ...