Deep in the folds of the intestine, in microscopic pockets called crypts, a quiet surveillance system is always at work. Stem ...

Crypt-base-columnar cells are continuously dividing intestinal stem cells that generate IECs, which are composed by distinct specialised cell types that play different functions: Enterocytes (in the ...

In vivo, the intestinal epithelium interacts with the neighboring environment through complex crosstalk, which involves components such as the immune system, tissue microenvironment, and gut microbes.

We often treat intestinal infections as an episode: a few days of symptoms, elimination of the pathogen, and recovery. In this view, the disease has a clear beginning and end. However, patient ...

A recent study in Nature Microbiology investigated how Salmonella typhimurium targets the gut epithelium and localizes to the follicle-associated epithelium (FAE) of the small intestine. The human gut ...