Individual mammalian cells contain billions of protein molecules, which must be synthesized, deployed, and removed with ...

Protein degradation in the cell can be carried out by an enzyme complex called the proteasome. Writing in Nature, Goldberg et al. 1 reveal that the proteasome is more than just a protein-degradation ...

Located at the cellular interface, membrane proteins play critical regulatory roles in the signaling between a cell and its interacting environment, making them popular and ideal drug targets.

Proteins, the pillars of cellular function, often assemble into 'complexes' to fulfill their functions. A study reveals why this assembly often begins during the very process of protein synthesis or ...

The diagram illustrates the key stages of protein synthesis in a eukaryotic cell. It begins with transcription to produce pre-mRNA in the nucleus (1), followed by post-transcriptional modification (2) ...

Cells do what proteins tell them to do. But sequencing DNA or running microarrays won’t reveal a protein’s mandate. During and after translation, enzymes, lipids, proteins, and sugars decorate the ...

Jessica Kramer, left, and Thomas McParlton observe the size of ice crystals in a sample treated with their protein in their lab at the University of Utah. Anyone who has experienced freezer burn knows ...

These proteins depend on their partner because they are rapidly degraded if they are not combined into complexes as soon as they are made. Proteins, the pillars of cellular function, often assemble ...