Am J Health Syst Pharm. 2010;67(4):274-279. The objectives of this study were to develop and test an adjustment factor (AF) for estimating aminoglycoside clearance (CL amino) from the Cockcroft–Gault ...

The common use of the Cockcroft-Gault equation suggests that it will remain the method of choice for drug dosing in patients with renal impairment. In contrast, the MDRD4 equation is likely to remain ...

In this issue of the Journal of Clinical Oncology, Takimoto et al 8 report the results of a phase I and pharmacokinetic study of oxaliplatin in 37 adult cancer patients with renal impairment. This ...

Incorporating β2-microglobulin and β-trace protein filtration markers may improve GFR estimation in patients with solid tumors. Adding the novel endogenous filtration markers β2-microglobulin and ...

Changing the Natural History of Non–Small-Cell Lung Cancer Through Upfront Programmed Death Protein 1/Programmed Death-Ligand 1 Blockade In the article accompanying this editorial, Janowitz et al 1 ...

Over one in four adults over the age of 65 may have chronic kidney disease (CKD) defined as a reduced kidney function. While serum creatinine remains the most practical biomarker for estimation of ...

Please provide your email address to receive an email when new articles are posted on . Research from Kaiser Permanente supports the use of cystatin C tests as an alternative to creatinine-based tests ...

The need for dialysis depends on symptoms, the cause of the problem, and overall kidney function, not just one lab result ...