A single enzyme that can generate all four nucleoside triphosphates, the building blocks of ribonucleic acid (RNA), has been ...

A single enzyme that can generate all four nucleotide triphosphates, the building blocks of ribonucleic acid (RNA), was ...

CHANGES of volume accompanying enzyme hydrolysis have been utilised by Sreenivasaya and Sastry 1 to follow the kinetics of enzyme action by means of the dilatometer. The procedure employed in the ...

Researchers defined the structure of a substrate-bound iron 2-oxoglutarate (Fe/2OG) enzyme to explore whether these enzymes could be used to create a wide array of molecules. They saw that Fe/2OG ...

Chemists at MIT have introduced an engineered biosynthetic enzyme that accepts a wider range of substrates into periwinkle plant culture to make unnatural analogs of alkaloids (Nat. Chem. Biol., DOI: ...

In biology, enzymes have evolved over millions of years to drive chemical reactions. Scientists have now derived universal rules to enable the de novo design of optimal enzymes. As an example, they ...

Pericyclic reactions, in which electrons move in concert to rearrange a molecule’s structure, are standard tools for synthetic chemists. But examples of such transformations in nature are fairly rare.

Researchers at the University created an artificial intelligence model named EZSpecificity to test how well certain enzymes and substrates bind to each other. Huimin Zhao and Diwakar Shukla, ...

Real-time measurement of the initial stage of an enzyme–substrate reaction is essential for reproducible enzyme kinetics data. Automated direct-flow injection systems couple with various detection and ...