The cytochromes P450 (CYPs) are the main enzyme family for metabolism of therapeutic drugs. CYP3A4 is the most active drug metabolizing CYP, and it plays a prominent role in adverse drug-drug ...

Enzyme inhibitors play a pivotal role in pharmaceutical and nutraceutical industries. The primary understanding of the action of inhibitors helps pharmacologists during the design process for ...

Advancement of techniques to achieve efficient and relevant outcomes occurs when technologies merge at critical moments. In the pharmaceutical industry, techniques such as in silico drug design and ...

A near-universal way to measure enzyme inhibition. ScienceDaily. Retrieved December 20, 2025 from www.sciencedaily.com / releases / 2018 / 03 / 180301103613.htm McGill University. "A near-universal ...

This is a preview. Log in through your library . Abstract The effects of various inhibitors of protein and nucleic acid synthesis on the development of invertase activity and increased nucleolar ...

Drugs are metabolized in the liver using several enzyme-catalyzed processes. These enzymes are collectively referred to as the hepatic microsomal enzyme system, and they are usually present in the ...

Criteria defining the duration of chemoreduction with focal treatment in retinoblastoma: A retrospective analysis. Background: Caffeine is a radio- and chemo-sensitizing agent acting by inhibiting ATM ...

Scientists have discovered the first selective inhibitors of an important set of enzymes. The new inhibitors, and chemical probes based on them, now can be used to study the functions of enzymes known ...

Putting the brakes on an enzyme might rescue neurons that are dying due to a type of Parkinson’s disease that’s caused by a single genetic mutation, according to a new Stanford Medicine-led study ...

This is a preview. Log in through your library . Abstract Time-courses of light-induced activities of enzymes relating to anthocyanin formation were studied. Phenylalanine ammonia-lyase (PAL), ...