Although it is an important technology for studying genomes, DNA sequencing was initially accomplished in 1977 by Frederick Sanger. Since its conception, the technology has developed rapidly. Alvaro G ...

In a way, sequencing DNA is very simple: There's a molecule, you look at it, and you write down what you find. You'd think it would be easy—and, for any one letter in the sequence, it is. The problem ...

In his Nobel Prize acceptance speech in 1980, genomics pioneer Fred Sanger described science as “a voyage of discovery into ...

Scientists have developed a new technique that could change how we design DNA for ...

Model predicts effect of mutations on sequences up to 1 million base pairs in length and is adept at tackling complex ...

SAVANA uses a machine learning algorithm to identify cancer-specific structural variations and copy number aberrations in long-read DNA sequencing data. The complex structure of cancer genomes means ...

Sequencing an entirely complete human genome has been the work of decades. Twenty years ago, the Human Genome Project (HGP) declared their work finished, with an asterisk. Even a decade later, fully ...

Current clinical challenges in Hodgkin lymphoma (HL) include difficult-to-treat relapsed/refractory disease and considerable long-term toxicities of treatment. Since clinical risk factors lack ...

Daniel Svensson and Anna-Mia Johansson take a break from DNA extractions to discuss new results. Both are research engineers at the Department of Ecology, Environment and Geoscience, Umeå University, ...