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Study unveils mechanisms driving axonal accumulation of TDP-43 and associated nerve damage in ALS
Past neuroscience studies have identified a TAR DNA-binding protein that plays a key role in ALS, known as TDP-43. This protein, which generally regulates RNA processing (i.e., how genetic information ...
Analyzing molecular changes in two types of peripheral nerves that are affected in diabetic peripheral neuropathy – the sural, which carry sensory signals, and the tibial, which carry both sensory and ...
A deep-learning model trained on optical coherence tomography scans of the optic nerve head reliably distinguished among various types of optic nerve damage, such as glaucoma, non-arteritic anterior ...
WINSTON-SALEM, N.C., Oct. 29, 2025 — Scientists at Wake Forest University School of Medicine, in collaboration with researchers at Weill Cornell Medicine, have made a breakthrough in understanding why ...
In a paper published in the journal Neuron, researchers report that a mechanism involving the enzyme Tiam1 in dorsal horn excitatory neurons of the spinal cord both initiates and maintains neuropathic ...
Nerve damage is one of the most common and burdensome complications of diabetes. Millions of patients worldwide suffer from pain, numbness, and restricted movement, largely because damaged nerve ...
Scientists have discovered a new chemical that could help heal nerve damage, according to research published Wednesday in the journal Nature, which offers early hope for one day reversing the ...
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