Precision and timing of gene expression is essential for normal biological functions and, when disrupted, can lead to many ...
The SWI/SNF Ig-Fold for Transcription Factor Interactions or 'SWIFT' domain on mSWI/SNF chromatin remodeling complexes engage ...
Study highlights importance of cancer driver biology in translating results from lab to patients -- -- Findings validate proprietary OncoSLX ...
Chromatin remodelers are ATP-dependent motor proteins that dynamically reorganize chromatin architecture, playing essential roles in gene expression, development, and immune function. Dysregulation of ...
Scientists at St. Jude Children's Research Hospital have revealed previously unappreciated roles for the retrotransposon LINE ...
Scientists at St. Jude Children's Research Hospital have revealed previously unappreciated roles for the retrotransposon LINE-1 in shaping the cancer genome structure and regulation.
A Northwestern Medicine study has revealed a previously unknown connection between two fundamental cellular processes, ...
This Brush Up is sponsored by Cayman Chemical. Learn more about chemical inhibitors of histone modification. Histone modification affects how tightly DNA wraps around histone proteins, yielding ...
Cancer researchers have long treated genetic chaos and epigenetic rewiring as separate engines of disease, two parallel ...