Jason Selvey died six years before his son, Daniel, due to the rare genetic illness Alagille Syndrome ...

A team of researchers at Baylor College of Medicine, UMass Chan Medical School and Cincinnati Children's Hospital Medical Center has developed a new treatment that could change the outlook for ...

Alagille syndrome is a rare multisystem disorder that primarily affects the liver, heart, and kidneys, and is most frequently associated with pathogenic mutations in the JAG1 gene, with a smaller ...

Alagille syndrome, a genetic disease estimated to affect 1 in 30,000 individuals, is caused by mutations in the gene JAG1 in most cases. The mutations affect multiple organs including the liver where ...

Research led by Associate Professor Duc Dong, Ph.D., has shown for the first time that the effects of Alagille syndrome, an incurable genetic disorder that affects the liver, could be reversed with a ...

An Ipsen drug developed to treat the severe itching that accompanies certain liver disorders is now FDA approved for treating this complication in patients with Alagille syndrome. It’s the second ...

'We shouldn't lose children before ourselves.' ...

Ipsen receives CHMP positive opinions for Iqirvo ® (elafibranor) in Primary Biliary Cholangitis and Kayfanda ® (odevixibat) in Alagille Syndrome, two rare cholestatic liver diseases PARIS, FRANCE, 26 ...

A drug to treat severe itching in patients with Alagille syndrome should be granted a marketing authorization in the European Union under what the European Medicines Agency (EMA) termed exceptional ...

AMBER Selvey’s husband Jason went to bed with a mild cold in 2017 – but she woke up to him ‘convulsing and not breathing properly’. The 47-year-old was suffering heart failure and passed away soon ...

Amber now fears her other children will meet the same tragic fate as her husband and son AMBER Selvey’s husband Jason went to bed with a mild cold in 2017 – but she woke up to him ‘convulsing and not ...