Pro Bowl defensive tackle DeForest Buckner was activated off injured reserve and will play Monday night when the Indianapolis Colts face the San Francisco 49ers.

The San Francisco 49ers offense is cruising and they were dominant in a win over the Indianapolis Colts. Here are the highlights.

Philip Rivers starts again when he takes on the ferocious 49ers on "Monday Night Football." Here's score, highlights, stats and more for Colts-49ers.

Something Purdy had in common with 44-year-old Philip Rivers on Monday — mental sharpness, which came in handy in a big Monday night win.

This article was originally published on www.si.com/onsi/athlete-lifestyle as Philip Rivers’ wife Tiffany, 10 kids take up entire suite for Colts vs. 49ers game.

With Week 16 in the books, a bit more clarity has been brought to the 2026 NFL Playoff picture. The bracket is far from set, however, even with 14 teams officially eliminated from contention with two games left to play.

Brock Purdy stats: 49ers QB makes MNF history with career game vs. Colts originally appeared on The Sporting News. Add The Sporting News as a Preferred Source by clicking here.

It's always a terrific thing when the punter is never called upon. That is exactly what happened to the San Francisco 49ers in their 48-27 win against the India